Figure 5.

Genes with different phylogenetic affinities in the lipopolysaccharide biosynthesis operon of Methanothermobacter thermoautotrophicus and Deinococcus radiodurans. (a) Organization of the lipopolysaccharide biosynthesis operon in different prokaryotes. COG1091 - dTDP-4-dehydrorhamnose reductase; COG1209 dTDP-glucose pyrophosphorylase; COG1898 - dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes; COG1088 - dTDP-D-glucose 4,6-dehydratase. The designations are as in Figure 1a. For species abbreviations, see Materials and methods. (b-e) Unrooted maximum-likelihood tree for RfbB (b), RfbC (c), RfbA (d) and RfbD (e); the designations are as in Figure 1b.