Table 1 |
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Substitution rates versus Ka/Ks ratios in duplicate genes |
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| Different amino-acid substitution rates* |
Equal amino-acid substitution rate† |
Total |
|
|
|
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| Different Ka/Ks ratios‡ |
54 |
11 |
65 |
| Equal Ka/Ks ratio§ |
91 |
94 |
185 |
| Total |
145 |
105 |
250 |
|
|
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A 2 × 2 chi-square test. χ2 = 12.78, df = 1, p < 0.001. The null hypothesis is that the number of pairs with different Ka/Ks ratios is independent of the number of pairs with different amino-acid substitution rates. The values are the observed number of pairs for each category; for example, there are 54 pairs with both different Ka/Ks ratios and different amino-acid substitution rates. The amino-acid substitution rates (or the Ka/Ks ratios) in the two duplicate genes are considered different only if the difference is statistically significant. *Gene pairs with different amino-acid substitution rates between the two duplicates. †Gene pairs with equal amino-acid substitution rates between the two duplicates. ‡Gene pairs with different Ka/Ks ratios between the two duplicates. §Gene pairs with equal Ka/Ks ratios between the two duplicates. |
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Zhang et al. Genome Biology 2003 4:R56 doi:10.1186/gb-2003-4-9-r56 |
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