Figure 9.

Identification of two novel genes linked to the arabinogalactan biosynthesis pathway, an important target of M. tuberculosis specific drugs. Based on the close proximity of adjacent genes (Operon method) and the functional linkage established by the Rosetta Stone method, we infer that Rv1503c and Rv1504c may be organized into a common operon. Both genes also have functional links to the genes rfe and rmlB, important components in the arabinogalactan biosynthesis pathway.