Table 4

Summary of the number of functional linkages between M. tuberculosis genes established by each of the four prediction methods of this paper, alone and in combination

Method(s)
Functional links
Proteins

One method


Rosetta Stone
20,714
1,279
Gene Neighbor
15,550
1,658
Phylogenetic Profiles
67,684
1,815
Operon (≤100 bp)
8,468
2,870



Two methods


100 bp Operon and RS
414

100 bp Operon and PP
632

100 bp Operon and GN
1516




Three methods


100 bp Operon, RS and PP
186

100 bp Operon, RS and GN
246

100 bp Operon, PP and GN
472




All four methods


100 bp Operon, PP, GN and RS
138


PP, Phylogenetic Profile method; GN, conserved Gene Neighbor method; RS, Rosetta Stone method.

Strong et al. Genome Biology 2003 4:R59   doi:10.1186/gb-2003-4-9-r59

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