Genome Biology

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An integrated gene annotation and transcriptional profiling approach towards the full gene content of the Drosophila genome

M Hild, B Beckmann, SA Haas, B Koch, V Solovyev, C Busold, K Fellenberg, M Boutros, M Vingron*, F Sauer*, JD Hoheisel* and R Paro*

Genome Biology 2003, 5:R3 doi:10.1186/gb-2003-5-1-r3

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BioMed Central: 10 citations

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Hundreds of putatively functional small open reading frames in Drosophila

Emmanuel Ladoukakis, Vini Pereira, Emile G Magny, Adam Eyre-Walker, Juan Pablo Couso Genome Biology 2011, 12:R118 (25 November 2011)

The Drosophila genome contains hundreds of small open reading frames with putative functionality

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High-resolution transcription atlas of the mitotic cell cycle in budding yeast

Marina V Granovskaia, Lars J Jensen, Matthew E Ritchie, Joern Toedling, Ye Ning, Peer Bork, Wolfgang Huber, Lars M Steinmetz Genome Biology 2010, 11:R24 (1 March 2010)

A high resolution strand-specific transcriptional atlas of the budding yeast mitotic cell cycle, including both mRNA and non-coding RNA profiles.

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Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function

James C Costello, Mehmet M Dalkilic, Scott M Beason, Jeff R Gehlhausen, Rupali Patwardhan, Sumit Middha, Brian D Eads, Justen R Andrews Genome Biology 2009, 10:R97 (16 September 2009)

The first computational interaction network built from Drosophila melanogaster protein-protein and genetic interaction data allows the functional annotation of orphan genes and reveals clusters of functionally-related genes.

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Evidence of a tick RNAi pathway by comparative genomics and reverse genetics screen of targets with known loss-of-function phenotypes in Drosophila

Sebastian Kurscheid, Ala E Lew-Tabor, Manuel Rodriguez Valle, Anthea G Bruyeres, Vivienne J Doogan, Ulrike G Munderloh, Felix D Guerrero, Roberto A Barrero, Matthew I Bellgard BMC Molecular Biology 2009, 10:26 (26 March 2009)

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Functional and evolutionary analysis of alternatively spliced genes is consistent with an early eukaryotic origin of alternative splicing

Manuel Irimia, Jakob Rukov, David Penny, Scott Roy BMC Evolutionary Biology 2007, 7:188 (4 October 2007)

Method   Open Access

A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila

Ramanuj DasGupta, Kent Nybakken, Matthew Booker, Bernard Mathey-Prevot, Foster Gonsalves, Binita Changkakoty, Norbert Perrimon Genome Biology 2007, 8:R203 (28 September 2007)

A second generation dsRNA library was used to re-assess factors that influence the outcome of transcriptional reporter-based whole-genome RNAi screens for the Wnt/Wingless (wg) and Hedgehog (hh)-signaling pathways.

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Systematic interpretation of microarray data using experiment annotations

Kurt Fellenberg, Christian H Busold, Olaf Witt, Andrea Bauer, Boris Beckmann, Nicole C Hauser, Marcus Frohme, Stefan Winter, Jürgen Dippon, Jörg D Hoheisel BMC Genomics 2006, 7:319 (20 December 2006)

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Sex-specific expression of alternative transcripts in Drosophila

Lauren M McIntyre, Lisa M Bono, Anne Genissel, Rick Westerman, Damion Junk, Marina Telonis-Scott, Larry Harshman, Marta L Wayne, Artyom Kopp, Sergey V Nuzhdin Genome Biology 2006, 7:R79 (25 August 2006)

A genome-wide microarray analysis of sex-specific expression of alternative transcripts in Drosophila shows sexual dimorphism in transcript abundance for 53% of the genes.

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Canonical Wnt signaling: high-throughput RNAi widens the path

Anthony MC Brown Genome Biology 2005, 6:231 (31 August 2005)

Although Wnt signaling has been the subject of extensive genetic analysis in the past, some 200 genes have now been identified as candidate modulators of this pathway by a recent study using high-throughput RNAi screening.

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How many genes in a genome?

Brian Oliver, Benoit Leblanc Genome Biology 2003, 5:204 (22 December 2003)

A recent study of the Drosophila genome has added perhaps 2,000 genes to the predicted total, and raises a number of questions about how genome annotation data should be stored and presented.