Genome Biology

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Functional classification of proteins for the prediction of cellular function from a protein-protein interaction network

Christine Brun1, François Chevenet2, David Martin1, Jérôme Wojcik3, Alain Guénoche4 and Bernard Jacq1*

Author Affiliations

1 Laboratoire de Génétique et Physiologie du Développement, CNRS UMR6545, Parc Scientifique et Technologique de Luminy, Case 907, 13288 Marseille Cedex 9, France

2 Centre d'Etude sur le Polymorphisme des Micro-organismes, CNRS/IRD UMR 9926, 911 avenue Agropolis, BP 6450, 34394 Montpellier Cedex 5, France

3 Hybrigenics SA, 3/5 impasse Reille, 75014 Paris, France

4 Institut de Mathématiques de Luminy, CNRS UPR9016, Parc Scientifique et Technologique de Luminy, Case 907, 13288 Marseille Cedex 9, France

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Genome Biology 2003, 5:R6 doi:

Published: 15 December 2003

Additional files

Additional data file 1:

Composition of the 63 PRODISTIN classes. Numbers in column ''Cellular Role' Annotation' indicate founder proteins for each class (see Fig. 3 legend). When two 'Cellular Roles' are assigned to a same class, 1 and 2 indicate proteins annotated with the first one and/or the second class respectively. A question mark (?) marks proteins of unknown function. The class robustness index is indicated for each class

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Additional data file 2:

Details of the functional predictions and comparisons with predictions obtained by other means

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