Genome Biology
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MinireviewGlobal nucleosome distribution and the regulation of transcription in yeastSevinc Ercan1,2, Michael J Carrozza1 and Jerry L Workman1  1
Stowers Institute for Medical Research, 1,000 East 50th Street, Kansas City, MO 64110, USA 2
Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA author email corresponding author email
Genome Biology 2004,
5:243doi:10.1186/gb-2004-5-10-243
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| Published: |
30 September 2004 |
Subject areas: Molecular biology, Genome studies, Model organisms Abstract
Recent studies show that active regulatory regions of the yeast genome have a lower density of nucleosomes than other regions, and that there is an inverse correlation between nucleosome density and the transcription rate of a gene. This may be the result of transcription factors displacing nucleosomes. |