Genome Biology

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A comprehensive transcript index of the human genome generated using microarrays and computational approaches

Eric E Schadt*, Stephen W Edwards, Debraj GuhaThakurta, Dan Holder, Lisa Ying, Vladimir Svetnik, Amy Leonardson, Kyle W Hart, Archie Russell, Guoya Li, Guy Cavet, John Castle, Paul McDonagh, Zhengyan Kan, Ronghua Chen, Andrew Kasarskis, Mihai Margarint, Ramon M Caceres, Jason M Johnson, Christopher D Armour, Philip W Garrett-Engele, Nicholas F Tsinoremas and Daniel D Shoemaker*

Genome Biology 2004, 5:R73 doi:10.1186/gb-2004-5-10-r73

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Research article   Open Access

Comparison and consolidation of microarray data sets of human tissue expression

Jenny Russ, Matthias E Futschik BMC Genomics 2010, 11:305 (14 May 2010)

Research   Open Access Highly Accessed

High-resolution transcription atlas of the mitotic cell cycle in budding yeast

Marina V Granovskaia, Lars J Jensen, Matthew E Ritchie, Joern Toedling, Ye Ning, Peer Bork, Wolfgang Huber, Lars M Steinmetz Genome Biology 2010, 11:R24 (1 March 2010)

A high resolution strand-specific transcriptional atlas of the budding yeast mitotic cell cycle, including both mRNA and non-coding RNA profiles.

Research article   Open Access Highly Accessed

Conservation of core gene expression in vertebrate tissues

Esther T Chan, Gerald T Quon, Gordon Chua, Tomas Babak, Miles Trochesset, Ralph A Zirngibl, Jane Aubin, Michael JH Ratcliffe, Andrew Wilde, Michael Brudno, Quaid D Morris, Timothy R Hughes Journal of Biology 2009, 8:33 (16 April 2009)

High conservation of tissue-specific expression is found across vertebrates yet there is a lack of conservation in common regulatory sequences/signatures.

Research   Open Access Highly Accessed

Exploring the transcriptional landscape of plant circadian rhythms using genome tiling arrays

Samuel P Hazen, Felix Naef, Tom Quisel, Joshua M Gendron, Huaming Chen, Joseph R Ecker, Justin O Borevitz, Steve A Kay Genome Biology 2009, 10:R17 (11 February 2009)

Whole genome tiling array analysis reveals the extent of transcriptional oscillation for both coding and non-coding genes in regulating Arabidopsis thaliana circadian rhythms

Methodology article   Open Access

Deep analysis of cellular transcriptomes – LongSAGE versus classic MPSS

Lawrence Hene, Vattipally B Sreenu, Mai T Vuong, S Hussain I Abidi, Julian K Sutton, Sarah L Rowland-Jones, Simon J Davis, Edward J Evans BMC Genomics 2007, 8:333 (24 September 2007)

Research article   Open Access

A detailed transcript-level probe annotation reveals alternative splicing based microarray platform differences

Joseph C Lee, David Stiles, Jun Lu, Margaret C Cam BMC Genomics 2007, 8:284 (20 August 2007)

Methodology article   Open Access

An efficient pseudomedian filter for tiling microrrays

Thomas E Royce, Nicholas J Carriero, Mark B Gerstein BMC Bioinformatics 2007, 8:186 (7 June 2007)

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Discovery of tissue-specific exons using comprehensive human exon microarrays

Tyson A Clark, Anthony C Schweitzer, Tina X Chen, Michelle K Staples, Gang Lu, Hui Wang, Alan Williams, John E Blume Genome Biology 2007, 8:R64 (24 April 2007)

Comprehensive exon microarrays with a simple intra-gene normalization algorithm were used to detect human tissue-specific alternative splicing events, suggesting significant expression outside of known exons and well annotated genes and a high frequency of alternative splicing events.

Research   Open Access

Comparative analysis of genome tiling array data reveals many novel primate-specific functional RNAs in human

Zhaolei Zhang, Andy Pang, Mark Gerstein BMC Evolutionary Biology 2007, 7(Suppl 1):S14 (8 February 2007)

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Cis-regulatory variations: A study of SNPs around genes showing cis-linkage in segregating mouse populations

Debraj GuhaThakurta, Tao Xie, Manish Anand, Stephen W Edwards, Guoya Li, Susanna S Wang, Eric E Schadt BMC Genomics 2006, 7:235 (15 September 2006)

Method   Open Access

Detecting transcriptionally active regions using genomic tiling arrays

Gabor Halasz, Marinus F van Batenburg, Joelle Perusse, Sujun Hua, Xiang-Jun Lu, Kevin P White, Harmen J Bussemaker Genome Biology 2006, 7:R59 (19 July 2006)

A new method for designing and integrating genomic tiling array data is described and applied to Anopheles and human arrays.

Method   Open Access

Transcript copy number estimation using a mouse whole-genome oligonucleotide microarray

Mark G Carter, Alexei A Sharov, Vincent VanBuren, Dawood B Dudekula, Condie E Carmack, Charlie Nelson, Minoru SH Ko Genome Biology 2005, 6:R61 (30 June 2005)

An in-situ-synthesized 60-mer oligonucleotide microarray designed to detect transcripts from all mouse genes is presented. Exogenous RNA controls derived from yeast allow quantitative estimation of absolute endogenous transcript abundance

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Co-regulation of mouse genes predicts function

Jonathan B Weitzman Journal of Biology 2004, 3:19 (6 December 2004)