Genome Biology

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Variation in alternative splicing across human tissues

Gene Yeo1,2, Dirk Holste1, Gabriel Kreiman2 and Christopher B Burge1*

  • * Corresponding author: Christopher B Burge cburge@mit.edu

  • † Equal contributors

Author Affiliations

1 Department of Biology, Center for Biological and Computational Learning, Massachusetts Institute of Technology, Cambridge, MA 02319, USA

2 Department of Brain and Cognitive Sciences, Center for Biological and Computational Learning, Massachusetts Institute of Technology, Cambridge, MA 02319, USA

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Genome Biology 2004, 5:R74 doi:10.1186/gb-2004-5-10-r74

Published: 13 September 2004

Additional files

Additional data file 1:

The average and median number of ESTs per gene and tissue, and the total number of genes per tissue using different minimum numbers of ESTs

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Open Data

Additional data file 2:

The average total number of AS genes and AS genes containing SEs, A3Es and A5Es using ESTs derived from normal, non-diseased tissues

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Open Data

Additional data file 3:

The number of constitutively spliced and AS genes, and AS genes containing SEs, A3Es and A5Es

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Open Data

Additional data file 4:

The average fractions of AS genes and average fractions of AS genes containing SEs, A3Es and A5Es using ESTs derived from normal, non-disease-derived tissues

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Open Data

Additional data file 5:

Categories of cDNA libraries and designated tissues derived from the MGC, IMAGE and CGAP

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Open Data

Additional data file 6:

The average lengths of ESTs that aligned to gene loci expressed in different tissues

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Additional data file 7:

Human splicing factors of SR, SR-related and hnRNP genes, corresponding Ensembl gene numbers and Affymetrix microarray probe identification numbers

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Open Data

Additional data file 8:

The distribution of the average Pearson correlation coefficient values across different tissues for expression levels of random sets of genes obtained from the Affymetrix microarray datat

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Open Data