Figure 3.

TF variation is higher in the majority of tissues compared to all genes. (a) Tissue distribution of alternatively spliced TFs versus tissue distribution of all alternatively spliced genes. For each tissue, the number of variant TF transcripts in tissue normalized by the total number of variant TF transcripts in MouSDB3 is represented as a blue bar. This number is computed as follows: t = number of variant TF transcripts in tissue; T = total number of variant TF transcripts; bar value = (t/T × 100). Red bars represent the number of variant transcripts of all genes in the tissue normalized by the total number of variant transcripts in MouSDB3. This value is computed as follows: a = total number of variant transcripts in tissue; A = total number of all variant transcripts in MouSDB3; bar value = (a/A × 100). (b) Fold differences in variant number of transcripts between TFs and all genes. This value is computed as follows: bar value = log₂((t/T)/(a/A)). Tissues are in descending order from highest to lowest fold difference of variation in TF versus variation in all genes. Tissue abbreviations: SG, salivary gland; SM, skeletal muscle; UB, urinary bladder; SC, spinal cord; AT, adipose tissue; MG, mammary gland.