Table 1

Mutation rates induced by HMPA treatment as assessed from white^- mutations at the transgene insertions on chromosomes 2 and 3

white⁺ loci

Brood

Mutation rate (× 10^-4)

Mosaicism at white⁺ loci

Both loci

2A + 2B and 3A

2.25

On chromosome 2

2A + 2B and 3A

2.68

1/14

On chromosome 3

2A + 2B and 3A

2.0

1/10

Both loci

2A + 2B

2.35

Both loci

3A

2.33

Numbers are based on 19 mutations recovered after screening of brood 1 has ceased. Two out of a total of 24 white^- mutants (five mutants were recovered while brood 1 was screened) were mosaic for the mutation. Mutations on chromosome 2 were slightly more common than mutations on chromosome 3; brood-2- and brood-3-derived mutations were equally frequent.

Nairz et al. Genome Biology 2004 5:R83   doi:10.1186/gb-2004-5-10-r83