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Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli

Brian J Peter16, Javier Arsuaga12, Adam M Breier3, Arkady B Khodursky4, Patrick O Brown5 and Nicholas R Cozzarelli1*

Author Affiliations

1 Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3204, USA

2 Mathematics Department, University of California, Berkeley, CA 94720, USA

3 Graduate Group in Biophysics, University of California, Berkeley, CA 94720, USA

4 Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, St. Paul, MN 55108, USA

5 Department of Biochemistry and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305-5307, USA

6 Current address: Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, UK

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Genome Biology 2004, 5:R87  doi:10.1186/gb-2004-5-11-r87

Published: 1 November 2004

Additional files

Additional data file 1:

Data on the induction of the SOS response to DNA damage

Format: PDF Size: 309KB Download file

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Additional data file 2:

Gene-expression ratios for all genes across all experiments

Format: XLS Size: 3.1MB Download file

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Open Data

Additional data file 3:

Gene-expression ratios for supercoiling-sensitive genes across all experiments

Format: XLS Size: 266KB Download file

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Open Data

Additional data file 4:

Data on the reproducibility of microarray measurement of RNA levels

Format: PDF Size: 753KB Download file

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Open Data