Bootstrapped GGM of the isoprenoid pathway with a cutoff at 0.8. The solid undirected edges connecting individual genes (in boxes) represent the GGM. Dotted directed edges mark the metabolic network, and are not part of the GGM. The grey shading indicates metabolic links to downstream pathways.
Wille et al. Genome Biology 2004 5:R92 doi:10.1186/gb-2004-5-11-r92