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List of complexes significantly represented in the phylogenetically distinct module cores |
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| Function |
Cores (rcc ≥ 5) |
Complexes |
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| Cell fate |
6 (2) |
Actin-associated motor protein, 431 |
| Energy |
4 (2) |
47, 346, Serine/threonine phosphoprotein phosphatase |
| Metabolism |
9 (3) |
521, GGTase II, OT |
| Cellular transport |
2 (2) |
Class C Vps, 239, 77, AP-3, AP-2 |
| Cell cycle |
7 (4) |
Tubulins, CA, AP, 3, OR, SCF-GRR1, SCF-CDC4, RI |
| Protein fate |
10 (5) |
Vps, Class C Vps, 71, 77, FT, GGTase I, 168, 651, OT, AP, 23 |
| Transport facilitation |
1 (1) |
TOM |
| Cell environment |
4 (3) |
STE5-MAPK, Kel1p/Kel2p, 521 |
| Protein synthesis |
5 (2) |
elF3, elF2B, elF2, 340, 339, 613 |
| Cell rescue |
3 (3) |
No complexes |
| Signaling |
2 (1) |
167, 308, 521 |
| Cell organization |
9 (6) |
272, 5, 71, 289, casein kinase II, 181, 167, Gim |
| Transcription |
9 (6) |
154, RM, RP, Ma, Cbf, Mb, 126, NSP1, TF, 178, CPK, 634, 160, CF |
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Numbers correspond to those complexes found by systematic analysis as described in MIPS [23]. Abbreviations: AP, anaphase-promoting complex; CA, chromatin-assembly complex; Cbf, Cbf1/Met4/Met28; CF, core factor; CPK, cAMP-dependent protein kinase; FT, farnesyltransferase; GGTase I, geranylgeranyltransferase I; GGTase II, geranylgeranyltransferase II; Ma, Met4/Met28/Met32; Mb, Met4/Met28/Met31; OR, origin-recognition complex; OT, oligosaccharyltransferase; RI, replication initiation complex; RM, RNase MRP; RP, RNase P; TF, TFIIIC; TOM, transport across the outer membrane complex; Vps, Vps35/Vps29/Vps2. Here, rcc is the ratio between the number of complex components being part of a core and the total number of complex constituents. | ||
Poyatos and Hurst Genome Biology 2004 5:R93 doi:10.1186/gb-2004-5-11-r93 |
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