Simplified biochemical reaction network of Bacillus subtilis central carbon metabolism. Gray arrows outline the biosynthesis of precursor amino acids that are indicated by their one-letter code. Amino acids in square brackets were not detected. Black dashed arrows illustrate the uptake of substrates. Black boxes highlight pathways or reactions that are affected in the mutants used (see also Table 1). G6P, glucose 6-phosphate; F6P, fructose 6-phosphate; T3P, triose phosphate; PGA, phosphoglycerate; PEP, phosphoenolpyruvate; PYR, pyruvate; OAA, oxaloacetic acid; MAL, malic acid; OGA, 2-oxoglutarate.
Zamboni and Sauer Genome Biology 2004 5:R99 doi:10.1186/gb-2004-5-12-r99