Genome Biology Volume 5 Issue 2 |
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MinireviewThe diversity of endothelial cells: a challenge for therapeutic angiogenesisEdward M Conway and Peter Carmeliet Center for Transgene Technology and Gene Therapy, Flanders Interuniversity Institute for Biotechnology, University of Leuven Gasthuisberg O&N, Herestraat 49, 3000 Leuven, Belgium author email corresponding author email
Genome Biology 2004,
5:207
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| Published: |
29 January 2004 |
Subject areas: Physiology, Development, Genome studies, Medicine Abstract
Vascular endothelia comprise a diverse population of cells that specialize in response to genetic programs and environmental cues to take on distinct roles in different vessels, tissues, and organs, and in response to pathophysiological stresses. Characterization of endothelial-cell diversity will facilitate the development of novel, highly specific and safe therapies for many diseases. |