Genome Biology Volume 5 Issue 2 |
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MinireviewSpreading silence with SidPeter van Roessel1,2 and Andrea H Brand1  1The Wellcome Trust/Cancer Research UK Gurdon Institute and Department of Genetics, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK 2Current address: Stanford University School of Medicine, Stanford, CA 94305, USA author email corresponding author email
Genome Biology 2004,
5:208
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| Published: |
30 January 2004 |
Subject areas: Genetics, Genome studies, Model organisms, Methods Abstract
RNA interference (RNAi) has been shown to spread from cell to cell in plants and in Caenorhabditis elegans, but it does not spread in other organisms, such as Drosophila. A recent report demonstrates that a membrane channel, encoded by the gene sid-1, is responsible for the spreading of RNAi between cells. |