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Deposited research article

Prediction for Target Sites of Small Interfering RNA Duplexes in SARS Coronavirus

Fengmin Ji1 and Liaofu Luo2,3*

Author Affiliations

1 Institute for Biological Science and Technology,Faculty of Sciences, North Jiaotong University, Beijing, 100044 China

2 Laboratory of Theoretical Biophysics, Faculty of Sciences and Technology, Inner Mongolia University, Hohhot, 010021 China

3 Center for Theoretical Biology, Peking University, Beijing, 100871 China

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Genome Biology 2004, 5:P6 doi:10.1186/gb-2004-5-2-p6


This is the first version of this article to be made available publicly.

Published: 16 January 2004

Abstract

RNA interference is used for SARS-related pharmaceutical research and development. Following bioinformatic method twenty seven 21~25 base-long sequence segments in SARS-CoV genome are predicted as the optimal target sites of small interfering RNA duplexes.