Versatile and open software for comparing large genomes

Stefan Kurtz¹, Adam Phillippy², Arthur L Delcher², Michael Smoot²^,3, Martin Shumway², Corina Antonescu² and Steven L Salzberg²

¹Center for Bioinformatics, University of Hamburg, Bundesstrasse 43, 20146 Hamburg, Germany

²The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA

³Current address: Department of Computer Science, University of Virginia, Charlottesville, VA 22904, USA

author email corresponding author email

Genome Biology 2004, 5:R12doi:10.1186/gb-2004-5-2-r12


Published:	30 January 2004

Subject areas: Bioinformatics, Genome studies, Evolution

Abstract

The newest version of MUMmer easily handles comparisons of large eukaryotic genomes at varying evolutionary distances, as demonstrated by applications to multiple genomes. Two new graphical viewing tools provide alternative ways to analyze genome alignments. The new system is the first version of MUMmer to be released as open-source software. This allows other developers to contribute to the code base and freely redistribute the code. The MUMmer sources are available at http://www.tigr.org/software/mummer webcite.