Table 1

Assignment of InterAct classes and models

Treatments
Light-carbon interactions


+C/-L
+C/+L
-C/+L
InterAct class
Interaction
Model
Examples of other classes in the same model

No change (0x)
Induced (3x)
Induced (3x)
011
None; responds only to light
None
110, -1-10, 0-1-1
Induced (5x)
Induced (10x)
Induced (5x)
121
Inductive
Independent (model 1)
Repressive (such as -1-2-1); antagonistic (such as -10-1)
No change (0x)
Induced (3x)
No change (0x)
010
Synergistic
Dependent (model 2)
010 (also synergistic)
Induced (5x)
Induced (5x)
Induced (5x)
111
Equal effect (whether separately or together)
Independent and Dependent (model 3)
C dominates (such as 221); L dominates (such as 122); suppressed (such as 210); Enhanced (such as -1-20)

For simplicity, the values for each condition that make up the InterAct classes reflect only whether one response is higher than another, not the amount by which it is increased with respect to the untreated (-C,-L) sample. For example, the threefold induction in the first row and the fivefold induction in the second row are both counted as 1 and the tenfold induction as 2. See text for further details. Modified from Thum et al. [2].

Reyes and Chua Genome Biology 2004 5:213