Genome Biology

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Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

Lorenzo F Sempere, Sarah Freemantle, Ian Pitha-Rowe, Eric Moss, Ethan Dmitrovsky and Victor Ambros*

Genome Biology 2004, 5:R13 doi:

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BioMed Central: 28 citations

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MiR-206-mediated dynamic mechanism of the mammalian circadian clock

Wei Zhou, Yan Li, Xia Wang, Lianqi Wu, Yonghua Wang BMC Systems Biology 2011, 5:141 (9 September 2011)

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Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients

Stefano Gambardella, Fabrizio Rinaldi, Saverio M Lepore, Antonella Viola, Emanuele Loro, Corrado Angelini, Lodovica Vergani, Giuseppe Novelli, Annalisa Botta Journal of Translational Medicine 2010, 8:48 (20 May 2010)

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Detecting microRNA activity from gene expression data

Stephen F Madden, Susan B Carpenter, Ian B Jeffery, Harry Björkbacka, Katherine A Fitzgerald, Luke A O'Neill, Desmond G Higgins BMC Bioinformatics 2010, 11:257 (18 May 2010)

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Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation

Tim R Mercer, Irfan A Qureshi, Solen Gokhan, Marcel E Dinger, Guangyu Li, John S Mattick, Mark F Mehler BMC Neuroscience 2010, 11:14 (5 February 2010)

Methodology article   Open Access Highly Accessed

RNA degradation compromises the reliability of microRNA expression profiling

David Ibberson, Vladimir Benes, Martina U Muckenthaler, Mirco Castoldi BMC Biotechnology 2009, 9:102 (21 December 2009)

Research article   Open Access Highly Accessed

Reciprocal regulation of microRNA and mRNA profiles in neuronal development and synapse formation

Sergei A Manakov, Seth GN Grant, Anton J Enright BMC Genomics 2009, 10:419 (8 September 2009)

Methodology article   Open Access Highly Accessed

Reproducibility of quantitative RT-PCR array in miRNA expression profiling and comparison with microarray analysis

Yongxin Chen, Jonathan AL Gelfond, Linda M McManus, Paula K Shireman BMC Genomics 2009, 10:407 (28 August 2009)

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Regulation of MicroRNA Biogenesis: A miRiad of mechanisms

Brandi N Davis, Akiko Hata Cell Communication and Signaling 2009, 7:18 (10 August 2009)

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Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a

Stefanie Slezak, Ping Jin, Lorraine Caruccio, Jiaqiang Ren, Michael Bennett, Nausheen Zia, Sharon Adams, Ena Wang, Joao Ascensao, Geraldine Schechter, David Stroncek Journal of Translational Medicine 2009, 7:39 (4 June 2009)

Methodology article   Open Access Highly Accessed

Analyzing miRNA co-expression networks to explore TF-miRNA regulation

Sanghamitra Bandyopadhyay, Malay Bhattacharyya BMC Bioinformatics 2009, 10:163 (28 May 2009)

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Identification and target prediction of miRNAs specifically expressed in rat neural tissue

You-Jia Hua, Zhong-Yi Tang, Kang Tu, Li Zhu, Yi-Xue Li, Lu Xie, Hua-Sheng Xiao BMC Genomics 2009, 10:214 (9 May 2009)

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Identification of suitable endogenous control genes for microRNA gene expression analysis in human breast cancer

Pamela A Davoren, Roisin E McNeill, Aoife J Lowery, Michael J Kerin, Nicola Miller BMC Molecular Biology 2008, 9:76 (21 August 2008)

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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

Joachim Silber, Daniel A Lim, Claudia Petritsch, Anders I Persson, Alika K Maunakea, Mamie Yu, Scott R Vandenberg, David G Ginzinger, C David James, Joseph F Costello, Gabriele Bergers, William A Weiss, Arturo Alvarez-Buylla, J Graeme Hodgson BMC Medicine 2008, 6:14 (24 June 2008)

MicroRNAs miR-124 and miR-137, which are down-regulated in human glioblastomas and astrocytomas but up-regulated during neuronal stem cell differentiation, can induce cell cycle arrest in glioblastoma multiforme cells, suggesting possible therapeutic potential.

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Individual mRNA expression profiles reveal the effects of specific microRNAs

Amit Arora, David AC Simpson Genome Biology 2008, 9:R82 (16 May 2008)

The effect of a microRNA on the levels of its target mRNAs can be measured within a single gene expression profile

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Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa

Carol J Loscher, Karsten Hokamp, Paul F Kenna, Alasdair C Ivens, Peter Humphries, Arpad Palfi, G Jane Farrar Genome Biology 2007, 8:R248 (22 November 2007)

MicroRNA expression profiling showed that the retina of mice carrying a rhodopsin mutation that leads to retinitis pigmentosa have notably different microRNA profiles from wildtype mice; further in silico analyses identified potential retinal targets for differentially regulated microRNAs.

Methodology article   Open Access Highly Accessed

Prediction and preliminary validation of oncogene regulation by miRNAs

Edyta Koscianska, Vesselin Baev, Konstantinia Skreka, Katerina Oikonomaki, Ventsislav Rusinov, Martin Tabler, Kriton Kalantidis BMC Molecular Biology 2007, 8:79 (18 September 2007)

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MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system

Marika Kapsimali, Wigard P Kloosterman, Ewart de Bruijn, Frederic Rosa, Ronald HA Plasterk, Stephen W Wilson Genome Biology 2007, 8:R173 (21 August 2007)

A comprehensive analysis of the neuroanatomical expression profiles of 38 abundant conserved miRNAs in developing and adult zebrafish brain was performed.

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Characterization of microRNA expression profiles in normal human tissues

Yu Liang, Dana Ridzon, Linda Wong, Caifu Chen BMC Genomics 2007, 8:166 (12 June 2007)

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microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder

Diana O Perkins, Clark D Jeffries, L Fredrik Jarskog, J Michael Thomson, Keith Woods, Martin A Newman, Joel S Parker, Jianping Jin, Scott M Hammond Genome Biology 2007, 8:R27 (27 February 2007)

Transcriptional profiling reveals a possible association between schizophrenia and altered miRNA expression

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Identification of rat lung-specific microRNAs by microRNA microarray: valuable discoveries for the facilitation of lung research

Yang Wang, Tingting Weng, Deming Gou, Zhongming Chen, Narendranath Chintagari, Lin Liu BMC Genomics 2007, 8:29 (24 January 2007)

Research article   Open Access

Target labelling for the detection and profiling of microRNAs expressed in CNS tissue using microarrays

Reuben Saba, Stephanie A Booth BMC Biotechnology 2006, 6:47 (12 December 2006)

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Non coding RNA and brain

Carlo Presutti, Jessica Rosati, Sara Vincenti, Sergio Nasi BMC Neuroscience 2006, 7(Suppl 1):S5 (30 October 2006)

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Unraveling transcriptional control and cis-regulatory codes using the software suite GeneACT

Tom Cheung, Yin Kwan, Micah Hamady, Xuedong Liu Genome Biology 2006, 7:R97 (25 October 2006)

GENEACT, a new software suite for the detection of evolutionarily conserved transcription factor binding sites or microRNAs from differentially expressed genes from DNA microarray data, is described.

Research article   Open Access

Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea

Nicole C Hank, Joan Shapiro, Adrienne C Scheck BMC Cancer 2006, 6:2 (4 January 2006)

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Identification of clustered microRNAs using an ab initio prediction method

Alain Sewer, Nicodème Paul, Pablo Landgraf, Alexei Aravin, Sébastien Pfeffer, Michael J Brownstein, Thomas Tuschl, Erik van Nimwegen, Mihaela Zavolan BMC Bioinformatics 2005, 6:267 (7 November 2005)

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MicroRNA profiling of the murine hematopoietic system

Silvia Monticelli, K Mark Ansel, Changchun Xiao, Nicholas D Socci, Anna M Krichevsky, To-Ha Thai, Nikolaus Rajewsky, Debora S Marks, Chris Sander, Klaus Rajewsky, Anjana Rao, Kenneth S Kosik Genome Biology 2005, 6:R71 (1 August 2005)

The first report of systematic miRNA profiling in cells of the hematopoietic system suggests that, in addition to regulating commitment to particular cellular lineages, miRNAs might have a general role in cell differentiation and cell identity.

Research article   Open Access

A population-based statistical approach identifies parameters characteristic of human microRNA-mRNA interactions

Neil R Smalheiser, Vetle I Torvik BMC Bioinformatics 2004, 5:139 (28 September 2004)

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Microarray analysis of microRNA expression in the developing mammalian brain

Eric A Miska, Ezequiel Alvarez-Saavedra, Matthew Townsend, Akira Yoshii, Nenad Šestan, Pasko Rakic, Martha Constantine-Paton, H Robert Horvitz Genome Biology 2004, 5:R68 (31 August 2004)

A microarray technology suitable for analyzing the expression of microRNAs and of other small RNAs was used to determine the microRNA expression profile during mouse-brain development and observed a temporal wave of gene expression of sequential classes of microRNAs.