Genome Biology

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MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins

Sebastian Maurer-Stroh*, Masaki Gouda, Maria Novatchkova, Alexander Schleiffer, Georg Schneider, Fernanda L Sirota, Michael Wildpaner, Nobuhiro Hayashi and Frank Eisenhaber

Genome Biology 2004, 5:R21 doi:10.1186/gb-2004-5-3-r21

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Research   Open Access

pkaPS: prediction of protein kinase A phosphorylation sites with the simplified kinase-substrate binding model

Georg Neuberger, Georg Schneider, Frank Eisenhaber Biology Direct 2007, 2:1 (12 January 2007)

Research   Open Access

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

Cemalettin Bekpen, Julia P Hunn, Christoph Rohde, Iana Parvanova, Libby Guethlein, Diane M Dunn, Eva Glowalla, Maria Leptin, Jonathan C Howard Genome Biology 2005, 6:R92 (31 October 2005)

A survey of p47 GTPases in several vertebrate organisms shows that humans lack a p47 GTPase-based resistance system, suggesting that mice and humans deploy their immune resources against vacuolar pathogens in radically different ways.

Software   Open Access

Refinement and prediction of protein prenylation motifs

Sebastian Maurer-Stroh, Frank Eisenhaber Genome Biology 2005, 6:R55 (27 May 2005)

Three prenylation motif predictors are presented that allow discrimination between proteins that are unique substrates of farnesyltransferase (FT) and those that can be alternatively processed by geranylgeranyltransferase I (GGT1).

Research   Open Access

Hidden localization motifs: naturally occurring peroxisomal targeting signals in non-peroxisomal proteins

Georg Neuberger, Markus Kunze, Frank Eisenhaber, Johannes Berger, Andreas Hartig, Cecile Brocard Genome Biology 2004, 5:R97 (30 November 2004)

Functional but silent peroxisomal targeting signals have been found in non- peroxisomal proteins. This discovery has important implications for sequence-based signal prediction and for evolution.

Methodology article   Open Access

Predicting N-terminal myristoylation sites in plant proteins

Sheila Podell, Michael Gribskov BMC Genomics 2004, 5:37 (17 June 2004)