Structural genomics of membrane proteins
1 Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, CA 94720, USA
2 National High Magnetic Field Lab and Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA
Genome Biology 2004, 5:215 doi:Published: 15 March 2004
Improvements in the fields of membrane-protein molecular biology and biochemistry, technical advances in structural data collection and processing, and the availability of numerous sequenced genomes have paved the way for membrane-protein structural genomics efforts. There has been significant recent progress, but various issues essential for high-throughput membrane-protein structure determination remain to be resolved.