Structural genomics of membrane proteins

Peter Walian¹, Timothy A Cross² and Bing K Jap¹

¹Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, CA 94720, USA

²National High Magnetic Field Lab and Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA

author email corresponding author email

Genome Biology 2004, 5:215


Published:	15 March 2004

Subject areas: Biochemistry and structural biology, Methods, Genome studies

Abstract

Improvements in the fields of membrane-protein molecular biology and biochemistry, technical advances in structural data collection and processing, and the availability of numerous sequenced genomes have paved the way for membrane-protein structural genomics efforts. There has been significant recent progress, but various issues essential for high-throughput membrane-protein structure determination remain to be resolved.