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Drosophila as an emerging model to study metastasis

Madhuri Kango-Singh1 and Georg Halder123*

Author affiliations

1 Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA

2 The Genes and Development Graduate Program, The University of Texas M. D. Anderson Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA

3 Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA

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Citation and License

Genome Biology 2004, 5:216  doi:

Published: 25 March 2004

Abstract

Metastasis is the primary cause of human cancer-related deaths. Two recent studies describe a system for testing how multiple genetic events synergize to promote neoplastic growth and metastasis in Drosophila, paving the way for systematic approaches to understanding metastasis using the powerful tools of Drosophila genetics.