Human and chimp methylation patterns

Differences in DNA methylation patterns between humans and chimpanzees. Enard W, Fassbender A, ... , Pääbo S, Olek A. Curr Biol 2004, 14:R148-R149.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2004-5-4-320.asp#Enard webcite

Activity-based protein profiling

Mapping enzyme active sites in complex proteomes. Adam GC, Burbaum J, Kozarich JW, Patricelli MP, Cravatt BF. J Am Chem Soc 2004, 126:1363-1368.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2004-5-4-320.asp#Adam webcite

Transcriptional activator targets identified by FRET

In vivo target of a transcriptional activator revealed by fluorescence resonance energy transfer. Bhaumik SR, Raha T, Aiello DP, Green MR. Genes Dev 2004, 18:333-343.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2004-5-4-320.asp#Bhaumik webcite

Onion ESTs

A unique set of 11,008 onion expressed sequence tags reveals expressed sequence and genomic differences between the monocot orders Asparagales and Poales. Kuhl JC, Cheung F, Yuan Q, Martin W, Zewdie Y, McCallum J, Catanach A, Rutherford P, Sink KC, Jenderek M, et al. Plant Cell 2004, 16:114-125.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2004-5-4-320.asp#Kuhl webcite

Gene organization and mutation rates

Functional bias and spatial organization of genes in mutational hot and cold regions in the human genome. Chuang JH, Li H. PLoS Biol 2004, 2:E29.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2004-5-4-320.asp#Chuang webcite

Genome Biologypaper reports
Genome Biology aims to highlight significant research articles newly published in other journals. From 2003, individual paper reports have been replaced by summaries of articles of interest to Genome Biology readers, taken from those highlighted by Faculty of 1000, a new online literature awareness tool published by BioMed Central. Faculty of 1000 systematically and comprehensively reviews the most interesting recent articles published in the biological sciences on the basis of recommendations of a faculty of over 1,400 selected leading researchers.