Table 1 |
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|
Duplications and syntenic breakpoints in the human genome compared with mouse |
|||||||||
| Total analyzed |
Duplication-positive counts* |
Duplication-positive bases |
|||||||
|
|
|
|
|||||||
| Number |
bp |
%† |
Number |
% |
p-value‡ |
bp |
% |
p-value‡ |
|
|
|
|||||||||
| Duplicated blocks |
1,643 |
72,151,679 |
2.6 |
NA |
NA |
NA |
NA |
NA |
NA |
| Break points |
461 |
83,985,399 |
3.1 |
122 |
26.5 |
< 0.0001 |
20,030,062 |
23.8 |
< 0.0001 |
| Between chromosomes |
163 |
42,496,016 |
1.5 |
43 |
26.4 |
< 0.0001 |
7,265,961 |
17.1 |
< 0.0001 |
| Different orientations |
298 |
41,489,383 |
1.5 |
79 |
26.5 |
< 0.0001 |
12,555,425 |
30.3 |
< 0.0001 |
|
|
|||||||||
|
*A positive breakpoint contained ≥ 10 kb duplicated sequence (continuous sequence).†Fraction of genome size (2,745,533,264 bp, which excludes highly duplicated pericentromeric and subtelomeric regions).‡p < 0.0001, simulated value never exceeded observed in 10,000 replicates. NA, not applicable. |
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|
Bailey et al. Genome Biology 2004 5:R23 |
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