Table 2

Comparison of human-mouse and human-rat breakpoints versus segmental duplication content

Duplicated

Unduplicated

Total

Number

%

Number

%

Number

Mouse-specific

29

29.9

68

70.1

97

Shared breakpoint

110

34.2

212

65.8

322

Undetermined*

12

28.6

30

71.4

42

Mouse-human breakpoints were classified as either shared with rat or specific to the mouse assembly. No significant difference in segmental duplication content was found when shared and mouse-specific breakpoints were compared. Chi-squared test (χ² = 0.5397, p = 0.4626). *Forty-two human-mouse breakpoints showed no evidence of conserved synteny within 1 Mb of the breakpoint when the human and rat genomes were compared.

Bailey et al. Genome Biology 2004 5:R23