Table 2

Comparison of human-mouse and human-rat breakpoints versus segmental duplication content


Duplicated
Unduplicated
Total


Number
%
Number
%
Number

Mouse-specific
29
29.9
68
70.1
97
Shared breakpoint
110
34.2
212
65.8
322
Undetermined*
12
28.6
30
71.4
42

Mouse-human breakpoints were classified as either shared with rat or specific to the mouse assembly. No significant difference in segmental duplication content was found when shared and mouse-specific breakpoints were compared. Chi-squared test (χ2 = 0.5397, p = 0.4626). *Forty-two human-mouse breakpoints showed no evidence of conserved synteny within 1 Mb of the breakpoint when the human and rat genomes were compared.

Bailey et al. Genome Biology 2004 5:R23  

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