Table 1

A summary of the families and superfamilies within Gene3D

Type of family

Proportion of non-singleton domains

Number of superfamilies

Number of close families

Number of folds

Known structure (CATH)

50%

1,277

93,571

759 + 54

Superfolds (all of known structure)

71,080

54

Unknown structure (Pfam)

33%

1,832

61,722

3,871

NewFam

17%

52,973

Total, excluding singletons:

208,266

4,684

Data are from [4]; NewFam denotes uncharacterized families. Around 60,000 singletons are excluded from the analysis. See the text for how the number of folds is estimated for the domains of unknown structure.

Grant et al. Genome Biology 2004 5:107