Genome Biology

official impact factor 6.89

Open Access

Transcriptional regulation of protein complexes in yeast

Nicolas Simonis, Jacques van Helden, George N Cohen and Shoshana J Wodak*

Genome Biology 2004, 5:R33 doi:

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Research article   Open Access

Composite functional module inference: detecting cooperation between transcriptional regulation and protein interaction by mantel test

Chao Wu, Fan Zhang, Xia Li, Shihua Zhang, Jiang Li, Fei Su, Kongning Li, Yuqing Yan BMC Systems Biology 2010, 4:82 (10 June 2010)

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Evaluation of clustering algorithms for protein-protein interaction networks

Sylvain Brohée, Jacques van Helden BMC Bioinformatics 2006, 7:488 (6 November 2006)

Research article   Open Access Highly Accessed

Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network

Lan V Zhang, Oliver D King, Sharyl L Wong, Debra S Goldberg, Amy HY Tong, Guillaume Lesage, Brenda Andrews, Howard Bussey, Charles Boone, Frederick P Roth Journal of Biology 2005, 4:6 (1 June 2005)

The multiple complex biological interactions in a yeast cell can be mapped in a simple graphical form, enhancing our understanding of the networks of interaction by which components of a cell influence one another.

Research article   Open Access

Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals

Sven Nelander, Erik Larsson, Erik Kristiansson, Robert Månsson, Olle Nerman, Mikael Sigvardsson, Petter Mostad, Per Lindahl BMC Genomics 2005, 6:68 (9 May 2005)

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How biologically relevant are interaction-based modules in protein networks?

Juan F Poyatos, Laurence D Hurst Genome Biology 2004, 5:R93 (1 November 2004)

The authors present a method to identify modules within protein-interaction networks. Phylogenetic profiles are used to determine the biological relevance of the modules.