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Opinion

Metabolite profiling in plant biology: platforms and destinations

Joachim Kopka, Alisdair Fernie, Wolfram Weckwerth, Yves Gibon and Mark Stitt*

Author Affiliations

Max-Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, 14476 Golm, Germany

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Genome Biology 2004, 5:109  doi:10.1186/gb-2004-5-6-109

Published: 18 May 2004

Abstract

Optimal use of genome sequences and gene-expression resources requires powerful phenotyping platforms, including those for systematic analysis of metabolite composition. The most used technologies for metabolite profiling, including mass spectral, nuclear magnetic resonance and enzyme-based approaches, have various advantages and disadvantages, and problems can arise with reliability and the interpretation of the huge datasets produced. These techniques will be useful for answering important biological questions in the future.