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Common ground in the transcriptional profiles of wounds and tumors

Richard Grose

Author Affiliations

Cancer Research UK London Research Institute, 61 Lincoln's Inn Fields, London WC2A 3PX, UK

Genome Biology 2004, 5:228  doi:10.1186/gb-2004-5-6-228

Published: 26 May 2004

Abstract

Healing wounds and developing tumors are both sites of dynamic interactions between a variety of cell types. Recent microarray studies comparing wounds and tumors have identified characteristic similarities in gene expression that may prove to be useful for assessing cancer prognosis and for choosing subsequent treatment.