Table 3

START-domain-containing proteins from the animal kingdom, and from the multicellular protist Dictyostelium discoideum

Accession code

Locus

Other names

Organism

Structure

Size (aa)

START domain

Transmembrane segments


P49675

StarD1

StAR

Homo sapiens

START

285

69-281

-

Q9UKL6

StarD2

PCTP

Homo sapiens

START

214

7-213

-

CAA56489

StarD3

MLN64

Homo sapiens

START

445

235-444

4 (o52-74i94-116o123-145i153-169o)

Q99JV5

StarD4

CRSP

Homo sapiens

START

224

21-223

-

Q9NSY2

StarD5

-

Homo sapiens

START

213

1-213

-

P59095

StarD6

-

Homo sapiens

START

220

39-206

-

Q9NQZ5

StarD7

GTT1

Homo sapiens

START

295

62-250

-

BAA11506

StarD8

KIAA0189

Homo sapiens

SAM RhoGAP START

1132

927-1129

-

Q9P2P6

StarD9

KIAA1300

Homo sapiens

START

1820

1628-1813

-

Q9Y365

StarD10

SDCCAG28

Homo sapiens

START

291

26-226

-

Q9Y5P4*

StarD11

GPBP*

Homo sapiens

PH Ser-Rich START

624*

395-618

-

AAR26717*

StarD11

CERT*

Homo sapiens

PH Ser-Rich START

598*

365-589

-

Q96QB1

StarD12

DLC-1

Homo sapiens

SAM RhoGAP START

1091

879-1084

-

AAQ72791

StarD13

RhoGAP

Homo sapiens

SAM RhoGAP START

1113

900-1104

-

Q8WYK0

StarD14

CACH

Homo sapiens

4HBT 4HBT START

555

342-545

-

Q8WXI4

StarD15

THEA

Homo sapiens

4HBT 4HBT START

607

378-590

-

NP_609644

CG6565

LD05321p

Drosophila melanogaster

START

425

186-381

-

AAR19767

CG3522

Start1

Drosophila melanogaster

START

583

262-362

4 (o59-81i102-124o128-150i162-179o)

487-574

NP_648199

CG7207

GH07688

Drosophila melanogaster

601

386-596

-

NP_731907

CG31319

RhoGAP88C

Drosophila melanogaster

RhoGAP START

1017

806-1007

-

NP_492624

1K507

F52F12.7

Caenorhabditis elegans

START

241

34-237

-

NP_510293

X0324

K02D3.2

Caenorhabditis elegans

START

296

69-279

-

NP_499460

3M432

T28D6.7

Caenorhabditis elegans

START

322

61-262

-

NP_505830

5L607

C06H2.2

Caenorhabditis elegans

START

397

121-337

-

NP_498027

3F991

F26F4.4

Caenorhabditis elegans

START

447

197-446

4 (o23-45i65-87o96-118i128-150o)

NP_492762

1L133

F25H2.6

Caenorhabditis elegans

PH Ser-Rich START

573

338-567

-

NP_497695*

gei-1*

F45H7.2

Caenorhabditis elegans

RhoGAP START

722*

532-710

-

NP_497694*

gei-1*

F45H7.2

Caenorhabditis elegans

RhoGAP START

842*

652-830

-

BAC01051

BmCBP

CBP1

Bombyx mori

START

297

60-294

-

AAD37799

ChtA

FbxA

Dictyostelium discoideum

START F-Box WD40

1247

8-178

-


GenBank accession codes, locus, other names, and corresponding organism are given for each predicted protein. START domain-containing (StarD) nomenclature is given for the human proteins. The structure, total size in amino acids (aa), and position of the START domain are listed. Numbers of predicted transmembrane segments followed by the amino acid positions separated by 'i' if the loop is on the inside or 'o' if it is on the outside (in parentheses) are indicated. *There are two protein isoforms as the products of alternative splicing. The internal loop in the Start1 START domain was not included in the analysis. All proteins are supported by cDNA clones.

Schrick et al. Genome Biology 2004 5:R41   doi:10.1186/gb-2004-5-6-r41

Open Data