Table 3

START-domain-containing proteins from the animal kingdom, and from the multicellular protist Dictyostelium discoideum

Accession code
Locus
Other names
Organism
Structure
Size (aa)
START domain
Transmembrane segments

P49675
StarD1
StAR
Homo sapiens
START
285
69-281
-
Q9UKL6
StarD2
PCTP
Homo sapiens
START
214
7-213
-
CAA56489
StarD3
MLN64
Homo sapiens
START
445
235-444
4 (o52-74i94-116o123-145i153-169o)
Q99JV5
StarD4
CRSP
Homo sapiens
START
224
21-223
-
Q9NSY2
StarD5
-
Homo sapiens
START
213
1-213
-
P59095
StarD6
-
Homo sapiens
START
220
39-206
-
Q9NQZ5
StarD7
GTT1
Homo sapiens
START
295
62-250
-
BAA11506
StarD8
KIAA0189
Homo sapiens
SAM RhoGAP START
1132
927-1129
-
Q9P2P6
StarD9
KIAA1300
Homo sapiens
START
1820
1628-1813
-
Q9Y365
StarD10
SDCCAG28
Homo sapiens
START
291
26-226
-
Q9Y5P4*
StarD11
GPBP*
Homo sapiens
PH Ser-Rich START
624*
395-618
-
AAR26717*
StarD11
CERT*
Homo sapiens
PH Ser-Rich START
598*
365-589
-
Q96QB1
StarD12
DLC-1
Homo sapiens
SAM RhoGAP START
1091
879-1084
-
AAQ72791
StarD13
RhoGAP
Homo sapiens
SAM RhoGAP START
1113
900-1104
-
Q8WYK0
StarD14
CACH
Homo sapiens
4HBT 4HBT START
555
342-545
-
Q8WXI4
StarD15
THEA
Homo sapiens
4HBT 4HBT START
607
378-590
-








NP_609644
CG6565
LD05321p
Drosophila melanogaster
START
425
186-381
-
AAR19767
CG3522
Start1
Drosophila melanogaster
START
583
262-362
4 (o59-81i102-124o128-150i162-179o)






487-574

NP_648199
CG7207
GH07688
Drosophila melanogaster

601
386-596
-
NP_731907
CG31319
RhoGAP88C
Drosophila melanogaster
RhoGAP START
1017
806-1007
-








NP_492624
1K507
F52F12.7
Caenorhabditis elegans
START
241
34-237
-
NP_510293
X0324
K02D3.2
Caenorhabditis elegans
START
296
69-279
-
NP_499460
3M432
T28D6.7
Caenorhabditis elegans
START
322
61-262
-
NP_505830
5L607
C06H2.2
Caenorhabditis elegans
START
397
121-337
-
NP_498027
3F991
F26F4.4
Caenorhabditis elegans
START
447
197-446
4 (o23-45i65-87o96-118i128-150o)
NP_492762
1L133
F25H2.6
Caenorhabditis elegans
PH Ser-Rich START
573
338-567
-
NP_497695*
gei-1*
F45H7.2
Caenorhabditis elegans
RhoGAP START
722*
532-710
-
NP_497694*
gei-1*
F45H7.2
Caenorhabditis elegans
RhoGAP START
842*
652-830
-








BAC01051
BmCBP
CBP1
Bombyx mori
START
297
60-294
-
AAD37799
ChtA
FbxA
Dictyostelium discoideum
START F-Box WD40
1247
8-178
-

GenBank accession codes, locus, other names, and corresponding organism are given for each predicted protein. START domain-containing (StarD) nomenclature is given for the human proteins. The structure, total size in amino acids (aa), and position of the START domain are listed. Numbers of predicted transmembrane segments followed by the amino acid positions separated by 'i' if the loop is on the inside or 'o' if it is on the outside (in parentheses) are indicated. *There are two protein isoforms as the products of alternative splicing. The internal loop in the Start1 START domain was not included in the analysis. All proteins are supported by cDNA clones.

Schrick et al. Genome Biology 2004 5:R41   doi:10.1186/gb-2004-5-6-r41