Additional data file 1:

A figure showing determination of three concentrations of four different perturbing agents with growth inhibition equivalent to that of 50, 100, and 150 mM HU

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Additional data file 2:

A figure showing intrinsic growth of all deletion strains and example growth curves for synergistic and antagonistic interactions

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Additional data file 3:

A figure showing reproducibility of GI values from independent experiments

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Additional data file 4:

A figure showing a comparison between drug dilution and cell dilution with respect to the GI

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Additional data file 5:

A figure showing showing the correlation of GI values resulting from perturbation with HU and different drug inhibitors

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Additional data file 6:

A figure showing clustering sub-analysis (based on gene classifications) of GI data from HU-interacting deletion strains, under growth inhibition with other drugs

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Additional data file 7:

A table showing AUGC and GI data from the genome wide screen for HU interactions

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Additional data file 8:

A table showing a comparison of HU interactions found in different genome-wide screens

Format: XLS Size: 44KB Download file

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Additional data file 9:

A table showing AUGC and GI data from the retest of HU-interacting strains for growth on HU, cisplatin, miconazole, cycloheximide, and t-butyl hydrogen peroxide

Format: XLS Size: 182KB Download file

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Additional data file 10:

A table showing identity and annotation of genes depicted in Figure 4

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Additional data file 11:

A table showing detailed classification of HU-selected strains

Format: XLS Size: 111KB Download file

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Additional data file 12:

A table showing interaction index values for all HU-selected deletion strains

Format: XLS Size: 58KB Download file

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Additional data file 13:

A table showing AUGC and GI data from the genome wide HU screen in the homozygous diploid deletion set

Format: XLS Size: 1.4MB Download file

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Additional data file 14:

A table showing a a comparison of the MATa haploid and homozygous diploid HU 150 screens

Format: XLS Size: 625KB Download file

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Additional data file 15:

The legends to the figures and tables

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