Genome Biology

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Detecting DNA regulatory motifs by incorporating positional trends in information content

Katherina J Kechris4,1*, Erik van Zwet1,5, Peter J Bickel1 and Michael B Eisen3,2

Author Affiliations

1 Department of Statistics, University of California, Berkeley, CA 94720, USA

2 Department of Genome Sciences, Life Sciences Division, Ernest Orlando Lawrence Berkeley National Lab, Cyclotron Road, Berkeley, CA 94720, USA

3 Center for Integrative Genomics, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA

4 Current address: Department of Biochemistry and Biophysics, 600 16th Street 2240, University of California, San Francisco, CA 94143, USA

5 Current address: Mathematical Institute, University Leiden, 2300 RA Leiden, The Netherlands

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Genome Biology 2004, 5:R50 doi:10.1186/gb-2004-5-7-r50

Published: 24 June 2004

Additional files

Additional data file 1:

A pdf file giving a detailed account of the data for both the simulations and real data analysis, methods for selecting starting points, evaluation diagnostics and a discussion of the options used in BioProspector and Gibbs Motif Sampler

Format: PDF Size: 96KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 2:

A pdf file giving additional results for the sections 'Effect of the number of starting points' and 'Gibbs Motif Sampler'

Format: PDF Size: 68KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data