Email updates

Keep up to date with the latest news and content from Genome Biology and BioMed Central.

Minireview

Success for gene therapy: render unto Caesar that which is Caesar's

Jian Qiao, Rosa Maria Diaz and Richard G Vile*

Author Affiliations

Molecular Medicine Program and Department of Immunology, Guggenheim 18, Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA

For all author emails, please log on.

Genome Biology 2004, 5:237  doi:10.1186/gb-2004-5-8-237

Published: 29 July 2004

Abstract

Reports that two young children developed leukemia after being treated for immunodeficiency with their own retrovirally modified bone-marrow cells delivered a severe blow to confidence in gene therapy as a treatment. Two reports, published since the trial was initiated, now take away some of the mystery as to why these events happened and allay fears for the safety of gene therapy across all therapeutic applications.