Table 2 |
||||
|
Partial list of cis-DNA elements of IFN-induced proteins |
||||
|
Gene |
Position |
Strand |
Sequence |
Binding site |
|
|
||||
|
ACACA |
-1847 |
Rev |
GTTTCTTTTTC |
ISRE |
|
-3800 |
Rev |
AGTTTCGGATTC |
IRF-7 |
|
|
B2M |
-167 |
GAAAAGGAAAC |
ISRE |
|
|
-161 |
GAAACTGAAAAC |
IRF-7 |
||
|
-2738 |
Rev |
GCTTTCATTTTC |
ISRE/IRF-7 |
|
|
G1P2 |
-316 |
GAAAATGAAAC |
ISRE/IRF-7 |
|
|
-114 |
GAAAGGGAAACC |
ISRE/IRF-3 |
||
|
-108 |
GAAACCGAAAC(T) |
ISRE/IRF-3/IRF-7 |
||
|
GBP1 |
-128 |
Rev |
ACTTTCAGTTTC |
IRF-7 |
|
GSA7 |
185 |
Rev |
AATTTCATTTTC |
IRF-7 |
|
IFIT1 |
-143 |
Rev |
(A)GTTTCACTTTC |
ISRE/IRF-7 |
|
-405 |
GAAACTGAAAAT |
IRF-7 |
||
|
-2096 |
Rev |
AATTTCATTTTC |
IRF-7 |
|
|
IFIT4 |
-173 |
Rev |
(G)GTTTCATTTTC |
ISRE/IRF-7 |
|
-139 |
Rev |
(A)GTTTCACTTTC |
ISRE/IRF-7 |
|
|
ISG20 |
-86 |
GAAAGGAAAC |
ISRE |
|
|
140 |
GAAACTGAAAC |
ISRE |
||
|
KIAA0186 |
-609 |
GAAATGGAAAGC |
ISRE |
|
|
KIAA1276 |
-1048 |
GAATCCGAAAAC |
ISRE |
|
|
LAMB1 |
-3940 |
GAAAGGAAAGC |
ISRE |
|
|
LOC151636 |
-94 |
GAAACTGAAAC(T) |
ISRE/IRF-7 |
|
|
MX1 |
-101 |
Rev |
GTTTCGTTTC |
ISRE |
|
-56 |
Rev |
GTTTCATTTC |
ISRE |
|
|
NMI |
-78 |
GAAAGTGAAATT |
IRF-7 |
|
|
NUDT2 |
-746 |
TTCCCGGAA |
GAS |
|
|
-2530 |
Rev |
GTTTCCTTTC |
ISRE |
|
|
OAS3 |
-170 |
GAAACGAAAC |
ISRE |
|
|
-165 |
GAAACTGAAAGC |
ISRE/IRF-7 |
||
|
-34 |
GAAAACGAAACC |
ISRE/IRF-7 |
||
|
PCMT1 |
-1370 |
GAATTTGAAAAT |
IRF-7 |
|
|
PRKR |
-3617 |
GAAAGGAAAC |
ISRE |
|
|
-374 |
Rev |
GTTTCCTTTC |
ISRE |
|
|
RPLP0 |
-1089 |
GAAACGGAAAGT |
IRF-3 |
|
|
STAT1 |
39 |
Rev |
(A)GTTTCGCTTTC |
ISRE/IRF-3/IRF-7 |
|
UBE2L6 |
-1813 |
TTCCGGGAA |
GAS |
|
|
|
||||
|
44% of promoter sequences have at least one of the following consensus sequences: GAS, TTCCSGGAA; ISRE, GAAA(N){1,2}GAAA(G){0,1}C [16]; IRF-3, GAAASSGAAANY; IRF-7, GAAWNYGAAANY. |
||||
|
Yan et al. Genome Biology 2004 5:R54 doi:10.1186/gb-2004-5-8-r54 |
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