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POSaM: a fast, flexible, open-source, inkjet oligonucleotide synthesizer and microarrayer

Christopher Lausted email, Timothy Dahl email, Charles Warren email, Kimberly King email, Kimberly Smith email, Michael Johnson email, Ramsey Saleem email, John Aitchison email, Lee Hood email and Stephen R Lasky email

The Institute for Systems Biology, 1441 North 34th Street, Seattle, WA 98103, USA

author email corresponding author email

Genome Biology 2004, 5:R58doi:10.1186/gb-2004-5-8-r58

Published: 27 July 2004

Subject areas: Methods, Genome studies

Abstract

DNA arrays are valuable tools in molecular biology laboratories. Their rapid acceptance was aided by the release of plans for a pin-spotting microarrayer by researchers at Stanford. Inkjet microarraying is a flexible, complementary technique that allows the synthesis of arrays of any oligonucleotide sequences de novo. We describe here an open-source inkjet arrayer capable of rapidly producing sets of unique 9,800-feature arrays.


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