Table 1 |
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|
Genomic location of pCRMs and neighboring genes |
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| pCRM |
ID* |
Name |
CRM activity |
Arm |
pCRM start |
pCRM end |
pCRM length |
5' gene |
pCRM relative position |
3' gene |
pCRM relative position |
|
|
|
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| 1 |
PCE7001 |
runt stripe 3 |
+ |
X |
20,357,206 |
20,358,294 |
1,089 |
CG1338 |
-9,550 |
run |
-8,561 |
|
| 2 |
PCE7002 |
eve stripes 3/7 |
+ |
2R |
5,035,494 |
5,036,771 |
1,278 |
CG12134 |
3,713 |
eve |
-2,952 |
|
| 3 |
PCE7003 |
eve stripe 2 |
+ |
2R |
5,038,454 |
5,039,040 |
587 |
CG12134 |
6,673 |
eve |
-683 |
|
| 4 |
PCE7004 |
eve stripes 4/6 |
+ |
2R |
5,044,597 |
5,045,395 |
799 |
eve |
4,874 |
TER94 |
-4,398 |
|
| 5 |
PCE7005 |
hairy stripe 7 |
+ |
3L |
8,624,351 |
8,625,245 |
895 |
CG6486 |
16,118 |
h |
-9,423 |
|
| 6 |
PCE7006 |
hairy stripe 6 |
+ |
3L |
8,625,452 |
8,626,319 |
868 |
CG6486 |
17,219 |
h |
-8,349 |
|
| 7 |
PCE7007 |
hairy stripes 1,5 |
+ |
3L |
8,629,180 |
8,629,966 |
787 |
CG6486 |
20,947 |
h |
-4,702 |
|
| 8 |
PCE7008 |
kni upstream |
+ |
3L |
20,615,070 |
20,616,425 |
1,356 |
kni |
-1,169 |
CG13253 |
21,311 |
|
| 9 |
PCE7009 |
hb HZ1.4 |
+ |
3R |
4,526,315 |
4,527,521 |
1,207 |
hb |
-2,760 |
CG8112 |
403 |
|
|
|
||||||||||||
| 10 |
PCE8001 |
1 |
gt posterior domain |
+ |
X |
2,187,439 |
2,188,382 |
944 |
gt |
-1,704 |
tko |
12,366 |
| 11 |
PCE8010 |
2 |
odd stripes 3/6 |
+ |
2L |
3,601,750 |
3,602,509 |
760 |
odd |
-2,433 |
Dot |
-9,351 |
| 12 |
PCE8011 |
3 |
nub blastoderm |
+ |
2L |
12,605,345 |
12,606,039 |
695 |
CG15488 |
2,687 |
nub |
-1,178 |
| 13 |
PCE8024 |
4 |
ftz stripes 1/5 |
+ |
3R |
2,693,713 |
2,694,405 |
693 |
ftz |
3,667 |
Antp |
131,873 |
| 14 |
PCE8012 |
5 |
pdm2 neurogenic |
+ |
2L |
12,663,878 |
12,664,600 |
723 |
pdm2 |
2,875 |
pdm2 |
2,875 |
| 15 |
PCE8027 |
6 |
sqz neurogenic |
+ |
3R |
15,000,096 |
15,000,905 |
810 |
sqz |
10,137 |
CG14282 |
-1,833 |
|
|
||||||||||||
| 16 |
PCE8005 |
7 |
cluster_at_7A |
amb. |
X |
6,996,209 |
6,996,756 |
548 |
CG32725 |
-17,671 |
CG1958 |
-10,524 |
| 17 |
PCE8016 |
8 |
cluster_at_55C |
amb. |
2R |
13,354,407 |
13,355,109 |
703 |
CG14502 |
957 |
CG14502 |
957 |
| 18 |
PCE8020 |
9 |
cluster_at_70F |
amb. |
3L |
14,665,967 |
14,666,676 |
710 |
ome |
10,334 |
ome |
10,334 |
|
|
||||||||||||
| 19 |
PCE8006 |
13 |
cluster_at_7B |
- |
X |
7,239,486 |
7,240,124 |
639 |
CG11368 |
46,902 |
CG32719 |
13,096 |
| 20 |
PCE8008 |
15 |
cluster_at_8F |
- |
X |
9,457,631 |
9,458,375 |
745 |
btd |
24,460 |
Sp1 |
-33,567 |
| 21 |
PCE8013 |
17 |
cluster_at_34E |
- |
2L |
13,989,283 |
13,990,132 |
850 |
rk |
-5,879 |
bgm |
-5,767 |
| 22 |
PCE8014 |
18 |
cluster_at_36F |
- |
2L |
18,400,758 |
18,401,458 |
701 |
CG31749 |
36,362 |
RpS26 |
19,862 |
| 23 |
PCE8015 |
19 |
cluster_at_47A |
- |
2R |
5,664,440 |
5,665,094 |
655 |
psq |
45,904 |
psq |
45,904 |
| 24 |
PCE8017 |
20 |
cluster_at_56B |
- |
2R |
14,266,629 |
14,267,261 |
633 |
CG7097 |
24,156 |
CG7097 |
24,156 |
| 25 |
PCE8018 |
21 |
cluster_at_59B |
- |
2R |
17,995,894 |
17,996,609 |
716 |
CG32835 |
759 |
CG32835 |
759 |
| 26 |
PCE8019 |
22 |
cluster_at_67B |
- |
3L |
9,529,913 |
9,530,579 |
667 |
CG32048 |
10,499 |
CG32048 |
10,499 |
| 27 |
PCE8021 |
23 |
cluster_at_75C |
- |
3L |
18,339,914 |
18,340,665 |
752 |
grim |
-86,621 |
rpr |
6,617 |
| 28 |
PCE8022 |
24 |
cluster_at_76C |
- |
3L |
19,594,180 |
19,594,883 |
704 |
CG8786 |
-1,409 |
CG8782 |
4,923 |
| 29 |
PCE8023 |
25 |
cluster_at_84A |
- |
3R |
2,595,162 |
2,595,926 |
765 |
Ama |
6,847 |
Dfd |
-21,632 |
| 30 |
PCE8025 |
26 |
cluster_at_85C |
- |
3R |
4,944,607 |
4,945,444 |
838 |
pum |
117,315 |
pum |
117,315 |
| 31 |
PCE8026 |
27 |
cluster_at_88F |
- |
3R |
11,424,315 |
11,424,996 |
682 |
CG18516 |
-45,803 |
CG5302 |
-33,626 |
| 32 |
PCE8028 |
28 |
cluster_at_95C |
- |
3R |
19,757,908 |
19,758,531 |
624 |
Gdh |
950 |
Gdh |
950 |
|
|
||||||||||||
| 33 |
PCE8003 |
11 |
cluster_at_5C.1 |
- |
X |
5,658,504 |
5,659,131 |
628 |
CG3726 |
952 |
CG3726 |
952 |
| 34 |
PCE8004 |
12 |
cluster_at_5C.2 |
- |
X |
5,674,913 |
5,675,606 |
694 |
CG3726 |
17,361 |
CG3726 |
17,361 |
| 35 |
PCE8009 |
16 |
cluster_at_12E |
- |
X |
14,146,556 |
14,147,218 |
663 |
CG32600 |
93,317 |
CG32600 |
93,317 |
| 36 |
PCE8002 |
10 |
cluster_at_4B |
- |
X |
4,124,119 |
4,125,459 |
1,341 |
CG12688 |
2,032 |
CG32773 |
3,408 |
| 37 |
PCE8007 |
14 |
cluster_at_7F |
Unknown |
X |
8,350,658 |
8,351,315 |
658 |
Caf1-180 |
-5,486 |
oc |
38,281 |
|
|
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|
*IDs in this column are taken from [11]. Genomic locations of the 37 pCRMs identified in our previous genome search. All coordinates are from D. melanogaster Release 3 [68]. pCRMs 1-9 were reported prior to our original search, and we attempted to characterize 10-37 in the current study (we reported PCE8001 in our previous publication). pCRMs10-15 recapitulate endogenous expression patterns of embryonic genes, and 16-18 drive ambiguous (amb.) expression patterns, as described in the text. pCRMs 19-36 drove no detectable expression in the embryo, and pCRM 37 was not tested. Orthologous regions were identified in D. pseudoobscura for all but pCRMs 33-37. The 5' and 3' gene columns correspond to the closest transcription (or annotation) start 5' and 3' of the pCRM. If a pCRM is within an intron, only the intron-containing gene is reported and its name is given in italics. The names of genes with early anterior-posterior patterns are in bold. |
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|
Berman et al. Genome Biology 2004 5:R61 doi:10.1186/gb-2004-5-9-r61 |
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