Table 1 |
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|
Transcription factors that tend to associate with nucleosome-depleted promoters |
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| Transcription factor |
Pathway |
Number of targets |
Nucleosome-depleted |
Functionally cooperative |
|
|
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| Rap1 |
Biosynthesis |
291 |
35% |
|
| Fhl1 |
Biosynthesis |
137 |
48% |
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| Swi4 |
Cell cycle |
165 |
36% |
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| Hsf1 |
Environmental response |
114 |
35% |
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| Gat3 |
Metabolism |
119 |
31% |
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| Cin5 |
Environmental response |
200 |
23% |
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| Phd1 |
Metabolism |
138 |
25% |
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| Dal81 |
Metabolism |
70 |
34% |
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| Ndd1 |
Cell cycle |
122 |
26% |
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| Yap6 |
Environmental response |
123 |
26% |
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| Fkh2 |
Cell cycle |
145 |
24% |
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| Pdr1 |
Environmental response |
103 |
27% |
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| Ino4 |
Metabolism |
118 |
25% |
|
| Smp1 |
Environmental response |
99 |
27% |
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| Yap5 |
Environmental response |
113 |
26% |
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| Ash1 |
Development |
41 |
41% |
|
|
|
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|
Transcription factors are ranked according to the significance of their association with nucleosome-depleted promoters, as determined by a hypergeometric model. Shown are the 16 top-ranked factors along with relevant physiologic pathway, number of promoters bound [1], and percent of target promoters that are nucleosome-depleted. Factors found previously to be functionally cooperative are indicated [22]. |
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|
Bernstein et al. Genome Biology 2004 5:R62 doi:10.1186/gb-2004-5-9-r62 |
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