Table 2

The number of interactions, genes, novel genes and disease genes in the complete and core human interaction networks

Network
Interactions
Genes
Novel genes
Disease genes

Complete
71,496
6,231
1,482
448
Core
11,487
3,872
864
292

The complete network consists of all human protein interactions predicted by model organism protein-interaction datasets. The core network consists of all the human interactions predicted by the high-confidence subsets of each interaction network (see Materials and methods). Novel genes are defined as those without GO annotations. Disease genes are defined by the OMIM database [25], available from Ensembl [16].

Lehner and Fraser Genome Biology 2004 5:R63   doi:10.1186/gb-2004-5-9-r63