Table 4

Sources of model organism protein-interaction data

Dataset

Interactions

Type

Reference

URL

Fly

20,020

Two-hybrid

[5]

[26]

Worm

4,605

Two-hybrid

[6]

[27]

Yeast

78,391

Total

[11]

[11]

5,125

Two-hybrid

49,313

Complex purification

886

Genetic

23,844 (23,399)

In silico (In silico only)

The table lists the total number of interactions contained in each model organism dataset, together with the method used to identify interactions, the publication reference, and the website (URL) from which the interaction dataset was obtained. For each dataset, the non-redundant number of unique interactions between unambiguously identified proteins is shown. For the yeast interactions, the total number of interactions is shown, as well as the number of interactions identified using each detection method. In silico only are interactions only predicted by in silico methods without any confirmation from the experimental datasets.

Lehner and Fraser Genome Biology 2004 5:R63   doi:10.1186/gb-2004-5-9-r63