Table 5

V-ATPase genes that are enriched in tubule

Subunit

Copy number

Genes

Affymetrix reference

Signal

Enrichment


V1 sector

A

3

vha68-1 (CG12403)

142380_at

9 ± 2

0.5 ± 0.1

vha68-2 (CG3762)

146305_at

5,874 ± 79

4.2 ± 0.1

vha68-3 (CG5075)

146306_at

2 ± 0

0.04 ± 0.02

B

1

vha55 (CG17369)

153041_at

2,304 ± 74

2.7 ± 0.1

SFD (H)

1

vhaSFD (CG17332)

144191_at

2,671 ± 66

4.4 ± 0.2

C

1

vha44 (CG8048)

153422_at

1,400 ± 74

3.5 ± 0.1

D

3

vha36-1 (CG8186)

152480_at

2,846 ± 154

4.5 ± 0.4

vha36-2 (

    CG13167
)

147073_at

2 ± 0.4

0.1 ± 0.0

    CG8310

144407_at

29 ± 4

0.6 ± 0.09

E

1

vha26 (CG1088)

151930_at

6,416 ± 190

3.1 ± 0.3

F

2

vha14-1 (CG8210)

143625_at

3,722 ± 105

3.2 ± 0.2

vha14-2 (CG1076)

149368_at

5.6 ± 1.6

1.5 ± 1.1

G

1

vha13 (

    CG6213
)

144156_at

2,952 ± 68

3.3 ± 0.1

V0 sector

A

5

vha100-1 (CG1709)

153997_at

155 ± 8

0.8 ± 0.0

vha100-2 (CG7679, CG18617)

142661_at

3,718 ± 157

5.4 ± 0.3

vha100-3 (CG30329)

not on array

    CG12602

146249_at

306 ± 26

1.3 ± 0.1

vha100-4 (

    CG7678
)

141662_at

66 ± 3

0.24 ± 0.04

c

5

vha16 (CG3161)

141528_at

5,845 ± 215

2.6 ± 0.1

vha16-2 (CG32089)/vha16-3

148578_at

32 ± 7

1.4 ± 0.22

(CG32090)

vha16-4 (CG9013)

147341_at

18 ± 4

1.4 ± 0.6

vha16-5 (

    CG6737
)

146189_at

36 ± 7

0.6 ± 0.12

PPA1

2

vhaPPA1-1 (CG7007)

142158_at

1,895 ± 79

4.1 ± 0.2

(c")

vhaPPA1-2 (CG7026)

149926_at

57 ± 7

0.9 ± 0.1

M9.7

3

vhaM9.7-1 (CG11589)

154011_at

101 ± 9

1.8 ± 0.0

(e, H)

    CG1268

148161_at

14 ± 1

0.1±0.0

vhaM9.7-2 (CG7625)

149187_at

3,101 ± 127

2.9 ± 0.1

AC39

2

vhaAC39-1 (CG2934)

154279_at

2,082 ± 52

3.4 ± 0.1

(d)

vhaAC39-2 (

    CG4624
)

150428_at

13 ± 2

0.8 ± 0.12


All genes significantly similar to known human or yeast V-ATPase subunits were identified by BLAST search, extending our previously reported annotation of the V-ATPase family [53], by identifying the genes underlined above as V-ATPase subunits. For comparison, enrichment ratios significantly greater than 1 and signals over 1,000 are shown in bold. (vha16-2 and vha16-3 are in tandem repeat and share the same Affymetrix oligo set, and so cannot be distinguished here.)

Wang et al. Genome Biology 2004 5:R69   doi:10.1186/gb-2004-5-9-r69

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