Table 5 |
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|
V-ATPase genes that are enriched in tubule |
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| Subunit |
Copy number |
Genes |
Affymetrix reference |
Signal |
Enrichment |
|
|
|||||
| V1 sector |
|||||
| A |
3 |
vha68-1 (CG12403) |
142380_at |
9 ± 2 |
0.5 ± 0.1 |
| vha68-2 (CG3762) |
146305_at |
5,874 ± 79 |
4.2 ± 0.1 |
||
| vha68-3 (CG5075) |
146306_at |
2 ± 0 |
0.04 ± 0.02 |
||
| B |
1 |
vha55 (CG17369) |
153041_at |
2,304 ± 74 |
2.7 ± 0.1 |
| SFD (H) |
1 |
vhaSFD (CG17332) |
144191_at |
2,671 ± 66 |
4.4 ± 0.2 |
| C |
1 |
vha44 (CG8048) |
153422_at |
1,400 ± 74 |
3.5 ± 0.1 |
| D |
3 |
vha36-1 (CG8186) |
152480_at |
2,846 ± 154 |
4.5 ± 0.4 |
| vha36-2 (CG13167) |
147073_at |
2 ± 0.4 |
0.1 ± 0.0 |
||
| CG8310 |
144407_at |
29 ± 4 |
0.6 ± 0.09 |
||
| E |
1 |
vha26 (CG1088) |
151930_at |
6,416 ± 190 |
3.1 ± 0.3 |
| F |
2 |
vha14-1 (CG8210) |
143625_at |
3,722 ± 105 |
3.2 ± 0.2 |
| vha14-2 (CG1076) |
149368_at |
5.6 ± 1.6 |
1.5 ± 1.1 |
||
| G |
1 |
vha13 (CG6213) |
144156_at |
2,952 ± 68 |
3.3 ± 0.1 |
| V0 sector |
|||||
| A |
5 |
vha100-1 (CG1709) |
153997_at |
155 ± 8 |
0.8 ± 0.0 |
| vha100-2 (CG7679, CG18617) |
142661_at |
3,718 ± 157 |
5.4 ± 0.3 |
||
| vha100-3 (CG30329) |
not on array |
||||
| CG12602 |
146249_at |
306 ± 26 |
1.3 ± 0.1 |
||
| vha100-4 (CG7678) |
141662_at |
66 ± 3 |
0.24 ± 0.04 |
||
| c |
5 |
vha16 (CG3161) |
141528_at |
5,845 ± 215 |
2.6 ± 0.1 |
| vha16-2 (CG32089)/vha16-3 |
148578_at |
32 ± 7 |
1.4 ± 0.22 |
||
| (CG32090) |
|||||
| vha16-4 (CG9013) |
147341_at |
18 ± 4 |
1.4 ± 0.6 |
||
| vha16-5 (CG6737) |
146189_at |
36 ± 7 |
0.6 ± 0.12 |
||
| PPA1 |
2 |
vhaPPA1-1 (CG7007) |
142158_at |
1,895 ± 79 |
4.1 ± 0.2 |
| (c") |
vhaPPA1-2 (CG7026) |
149926_at |
57 ± 7 |
0.9 ± 0.1 |
|
| M9.7 |
3 |
vhaM9.7-1 (CG11589) |
154011_at |
101 ± 9 |
1.8 ± 0.0 |
| (e, H) |
CG1268 |
148161_at |
14 ± 1 |
0.1±0.0 |
|
| vhaM9.7-2 (CG7625) |
149187_at |
3,101 ± 127 |
2.9 ± 0.1 |
||
| AC39 |
2 |
vhaAC39-1 (CG2934) |
154279_at |
2,082 ± 52 |
3.4 ± 0.1 |
| (d) |
vhaAC39-2 (CG4624) |
150428_at |
13 ± 2 |
0.8 ± 0.12 |
|
|
|
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|
All genes significantly similar to known human or yeast V-ATPase subunits were identified by BLAST search, extending our previously reported annotation of the V-ATPase family [53], by identifying the genes underlined above as V-ATPase subunits. For comparison, enrichment ratios significantly greater than 1 and signals over 1,000 are shown in bold. (vha16-2 and vha16-3 are in tandem repeat and share the same Affymetrix oligo set, and so cannot be distinguished here.) |
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|
Wang et al. Genome Biology 2004 5:R69 doi:10.1186/gb-2004-5-9-r69 |
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