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Profiling gene expression in growth-arrested mouse embryos in diapause

Eiichi Hondo and Colin L Stewart*

Author Affiliations

Cancer and Developmental Biology Laboratory, National Cancer Institute, Division of Basic Science, National Cancer Institute at Frederick, Frederick, MD 21702, USA

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Genome Biology 2004, 6:202  doi:10.1186/gb-2004-6-1-202

Published: 21 December 2004

Abstract

In many mammalian species, embryonic cell proliferation can be reversibly arrested in an embryonic diapause at the time of embryo implantation. A recent report has identified changes in embryonic gene expression that are associated with, and may halt, embryonic cell proliferation.