Predicted HumanCyc pathway for arginine degradation. The computer icon in the upper-right corner indicates this pathway was predicted computationally. Neither enzyme names nor gene names are drawn adjacent to the first three reactions of this pathway to indicate that these steps are pathway holes, meaning no enzyme has been identified for these steps in the human genome. The graphic at the bottom indicates the positions of genes within this pathways on the human chromosomes. Moving the mouse over a gene in the webpage for this diagram will identify the gene and the chromosome.
Romero et al. Genome Biology 2004 6:R2 doi:10.1186/gb-2004-6-1-r2