Table 5

Comparison of known essential human nutrients with corresponding biosynthetic pathways in MetaCyc and in HumanCyc

Essential nutrient in humans

Biosynthetic pathway in MetaCyc?

Biosynthetic pathway inferred in humans?


Amino acids

Arginine

Y

N

Histidine

Y

N

Isoleucine

Y

N

Leucine

Y

N

Lysine

Y

N

Methionine

Y

N

Phenylalanine

Y

N

Threonine

Y

N

Valine

Y

N

Vitamins

Ascorbic acid (Vitamin C)

Y

N

Biotin (Vitamin H)

Y

N

Folic acid (Vitamin M)

Y

N

Niacin (Vitamin B3)

N

N

Pantothenic acid

Y

Y

Pyridoxine (Vitamin B6)

N

N

Riboflavin (Vitamin B2)

Y

N

Thiamine (Vitamin B1)

Y

N

Cobalamin (Vitamin B12)

Y

N

Retinol (Vitamin A)

N

N

Vitamin D

N

N

Tocopherol (Vitamin E)

N

N

Vitamin K

N

N


Note that a pathway cannot be predicted in HumanCyc if it does not exist in MetaCyc.

Romero et al. Genome Biology 2004 6:R2   doi:10.1186/gb-2004-6-1-r2

Open Data