Table 6

Pathways (including superpathways) that are common to human, bacteria and plant PGDBs

Class
Subclass
Pathway

Biosynthesis
Polyamines
Betaine biosynthesis


Polyamine biosynthesis

Fatty acids and lipids
Phospholipid biosynthesis


Fatty acid biosynthesis - initial steps


Fatty acid elongation - saturated

Cofactors, prosthetic groups, electron carriers
Pyridine nucleotide biosynthesis


Thioredoxin pathway


Glutathione biosynthesis


Pantothenate and coenzyme A biosynthesis


Pyridoxal 5'-phosphate salvage pathway


Polyisoprenoid biosynthesis


FormylTHF biosynthesis

Cell structures
Colanic acid building blocks biosynthesis


GDP-mannose metabolism

Carbohydrates
Gluconeogenesis


Trehalose degradation - low osmolarity

Aminoacyl-tRNAs
tRNA charging pathway

Amino acid biosynthesis
Proline biosynthesis I


Glycine biosynthesis I


Serine biosynthesis



Degradation
Sugars and polysaccharides
Glucose 1-phosphate metabolism


Galactose metabolism


Trehalose degradation - low osmolarity


Glycogen degradation


Ribose degradation

Other degradation
Removal of superoxide radicals

Nucleosides and nucleotides
(Deoxy)ribose phosphate metabolism

Fatty acids
Fatty acid oxidation pathway

Carboxylates, other
Acetate degradation

Amino acids, amines
L-serine degradation

Alcohols
Glycerol metabolism



Energy metabolism

Pyruvate dehydrogenase


TCA cycle - aerobic respiration


Glycolysis


Oxidative branch of the pentose phosphate pathway


Nonoxidative branch of the pentose phosphate pathway

HumanCyc, H. sapiens; EcoCyc, E. coli; AraCyc, A. thaliana. The pathways in the table are included in all three PGDBs.

Romero et al. Genome Biology 2004 6:R2   doi:10.1186/gb-2004-6-1-r2