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Wound healing and inflammation genes revealed by array analysis of 'macrophageless' PU.1 null mice

Lisa Cooper14, Claire Johnson2, Frank Burslem2 and Paul Martin13*

Author Affiliations

1 Department of Anatomy and Developmental Biology, University College London, London, WC1E 6BT, UK

2 Pfizer Global Research and Development, Sandwich, Kent, CT13 9NJ, UK

3 Departments of Physiology and Biochemistry, University of Bristol, Bristol, BS8 1TD, UK

4 Current Address: Molecular Neuroscience Group, School of Medicine, University of Birmingham, Birmingham, B15 2TH, UK

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Genome Biology 2004, 6:R5  doi:10.1186/gb-2004-6-1-r5

Published: 23 December 2004

Additional files

Additional data file 1:

An Excel file containing an annotated database for the 1,001 differentially expressed genes in the nine temporal gene clusters: activation, early effector, late effector, stop, early inflammatory, late inflammatory; inflammation-maintained, and excluded clusters 1 and 2. For each gene this database provides an Affymetrix ID and GenBank description, together with absolute fluorescence levels and absence/presence calls for each time point, and known functional information gained from GenBank and Swiss-Prot databases

Format: XLS Size: 1.1MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 2:

Line graphs displaying the temporal profile of the median expression levels at each time point to give a representation of excluded clusters 1 and 2

Format: PDF Size: 324KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 3:

A Word document listing the origins of the various RNA probes used in the in situ hybridization studies

Format: DOC Size: 28KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional data file 4:

An Excel file containing the raw data - absolute fluorescence levels and absence/presence calls - for all genes on the Affymetrix MGU74 arrays at all experimental time points

Format: XLS Size: 5.4MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data