Genome Biology

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Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice

Shixia Huang3,1,2*, Yi Li4,1,2, Yidong Chen5, Katrina Podsypanina1, Mario Chamorro1, Adam B Olshen6, Kartiki V Desai7,8, Anne Tann2, David Petersen7, Jeffrey E Green7 and Harold E Varmus1

Author Affiliations

1 Program in Cancer Biology and Genetics, Sloan-Kettering Institute, New York, NY 10021, USA

2 Breast Center, Baylor College of Medicine, Houston, TX 77030, USA

3 Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA

4 Department of Cell and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA

5 National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA

6 Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA

7 National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA

8 Johns Hopkins in Singapore Ltd, The Nanos, Singapore 138669, Republic of Singapore

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Genome Biology 2005, 6:R84 doi:10.1186/gb-2005-6-10-r84

Published: 30 September 2005

Additional files

Additional File 1:

A table listing genes differentially expressed between mammary tumors from MMTV-Wnt-1 and MMTV-Neu transgenic mice

Format: DOC Size: 619KB Download file

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Additional File 2:

A table listing genes differentially expressed between Ha-Ras mutant and Ha-Ras wild-type tumors in MMTV-Wnt-1 mice

Format: DOC Size: 51KB Download file

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Additional File 3:

A table listing genes differentially expressed between MMTV-Wnt-1-induced tumors in p53-null and in p53-wild-type background

Format: DOC Size: 88KB Download file

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Additional File 4:

A table listing genes differentially expressed between tumors from MMTV-Wnt-1 transgenic/Pten+/- mice with loss of heterozygosity at the Pten locus and tumors from Wnt-1 transgenic/Pten+/+ mice

Format: DOC Size: 78KB Download file

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Additional File 5:

A table listing genes differentially expressed between virgin mammary glands from nontransgenic mice and hyperplastic mammary glands from MMTV-Wnt-1 transgenic mice

Format: DOC Size: 310KB Download file

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Additional File 6:

A table listing genes expressed three-fold or higher in fat tissues than in mammary tumors from MMMTV-Wnt-1 and MMTV-Neu transgenic mice

Format: DOC Size: 360KB Download file

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Additional File 7:

A table listing genes differentially expressed between mammary tumors and hyperplastic mammary glands from MMTV-Wnt-1 transgenic mice

Format: DOC Size: 199KB Download file

This file can be viewed with: Microsoft Word Viewer

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