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Highly AccessReview

Large-scale approaches for glycobiology

Christopher T Campbell and Kevin J Yarema email

Department of Biomedical Engineering, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA

author email corresponding author email

Genome Biology 2005, 6:236doi:10.1186/gb-2005-6-11-236

Published: 3 November 2005

Subject areas: Biochemistry and structural biology, Cancer, Cell biology

Abstract

Glycosylation, the attachment of carbohydrates to proteins and lipids, influences many biological processes. Despite detailed characterization of the cellular components that carry out glycosylation, a complete picture of a cell's glycoconjugates remains elusive because of the challenges inherent in characterizing complex carbohydrates. This article reviews large-scale techniques for accelerating progress in glycobiology.


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